Bacteroides the Good, the Bad, and the Nitty-Gritty
By a variety of
measures, the species Homo sapiens is more microbial than human.
Microorganisms comprise only a small, albeit significant, percentage of the
body weight (between 2 and 5 pounds of live bacteria). However, in terms of
cell numbers, we are about 10% human and 90% bacterial
the number of genes in our microbiome may
exceed the number of human genes by two orders of magnitude making us
genetically 1% human and 99% bacterial! Consequently, bacteria play a major
role in bodily functions, including immunity, digestion, and protection against
disease Colonization of the human body by microorganisms occurs at the very
beginning of human life and many of these organisms become truly indigenous to
the host.
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